ESG News For Takeda Pharmaceutical Company Limited

First-of-its-Kind Research Collaboration for Takeda and Boston Medical Center with the Aim to Decarbonize the Health Care Value ChainThree-Year Collaboration to Tackle Carbon Emissions from Regulated Medical Waste, Including Pharmaceutical PackagingLearnings will be Shared to Scale Decarbonization Solutions Across the Health Care Value Chain

More Than 22,000 Takeda Employees Selected the FY2024 New Partners: Population Services International, Bulungula Incubator, Reach Out Cameroon, Seed Global Health and VillageReachTakeda’s Five New Partnerships Boost Total Global CSR Program Contributions to JPY 28.8 Billion (Approx. USD 199.1 million) Across 34 Diverse Partnerships Worldwide and extend our reach to an additional 2 million direct beneficiariesTakeda’s Global CSR Program Expects to Reach 27 Million People in 93 Countries by 2030

The New Expanded Partnership Will Aim to Support the Dismantling of Systemic Barriers to Equity and Help Strengthen the Health Workforce in MassachusettsThe Existing Global Partnership Has Provided Screening and Diagnostic Services to Over 8 Million People in Community Settings

Increases access to food for neighbors in need in Clayton County

FY23 Investment Brings Program Total to Nearly $55 Million, Welcoming Eight New Grant PartnersCompany Continues to Advance Equity in Under-Resourced Communities with a Focus on Nutrition and STEM EducationTakeda Publishes its Annual U.S. Community Impact Report Highlighting Program Progress

Pear Suite announces the launch of a statewide training initiative supported by HCAI’s Caring4Cal program.

Industry-first, multi-party agreements in China and India to unlock at least 70 megawatts of renewable power capacity for global supply chainsNew public-private collaboration to develop frameworks to measure the environmental impact of medicines and delivery of patient care

Takeda’s Five New Partnerships Boost Total Global CSR Program Contributions to JPY 24.2 Billion (Approx. USD 167.5 million) Since Program Inception in 2016.More Than 24,500 Takeda Employees Worldwide Participated in the Selection of the Five New Partnerships: Society for Family Health Rwanda, Relief International, Mercy Corps, University of Nairobi and Partners In Health.With This New Cohort of Partnerships, Takeda’s Global CSR Program Expects to Reach 25.2 Million People in 92 Countries by 2028.

Nationwide Collaboration will Harness Social Determinants of Health (SDOH) Data to Better Connect Patients with Affirming Providers and Vital Community Health Resources

Recap of CSR stories on Business Wire

FY22 Investment Brings Program Total to Nearly $40 Million, Adding 21 New Grant PartnersCompany Continues to Improve Equity Among Under-Resourced Communities Focusing on Areas of Health, Education, Environment and ProvidingFirst U.S. CSR Report, Takeda Cares for Communities, Highlights Program Efforts Since its FY21 Launch

The three-day event returns to fully in-person for the first time in more than three years, featuring 200+ speakers, including government officials, philanthropists, scientists, and more

Event will Highlight and Explore Collaborative Efforts to Overcome Inequities Faced by Minoritized Communities

Recap of CSR stories on Business Wire

Since its Launch in 2016, New Partnerships Bring Total Global CSR Program Contributions to JPY 19.7 Billion (Approx. USD 140.7 million) Across 24 Programs in 79 CountriesMore Than 23,000 Takeda Employees Voted on New Partnerships Selecting Ipas, Plan International, Pure Earth and United Nations Population Fund (UNFPA)Global CSR Program Partnerships Help Takeda Advance Disease Prevention, Empower the Health Workforce and Strengthen Health Systems Across the World

New Nonprofit Cybersecurity Portfolio commits $1M+ as part of Okta’s 3-year Nonprofit Technology Initiative

− Takeda is enhancing its Corporate Social Responsibility program with significant commitment to underrepresented communities in the U.S.− U.S. Program prioritizes health equity, climate resiliency, K-8 math literacy and food security across the country− 20 grantees selected as FY2021 program partners

- Global employees based across 80 countries and regions voted to support new partnerships with IntraHealth International, Jhpiego, Pathfinder International and the World Food Programme- New partnerships bring total Global CSR Program contributions to JPY 16.5 billion across 20 programs in 72 countries following launch in 2016- Global CSR Program partnerships help Takeda advance disease prevention measures, empower the health workforce and support health systems

Leaders and clinical improvers gather virtually to share new ideas and evidence-based approaches to improve population health and health equity

− Takeda employees worldwide voted to add Access to Health Fund and Bridges to Development as 2020 partners− With these new partners, Takeda's Global CSR Program contributions total JPY 12.3 billion (USD 112 million*) across 16 programs in more than 60 countries since its 2016 launch− Takeda’s founding mission to serve patients, wherever they are, drives its commitments to prevent disease and increase access to healthcare in partnership with the global community

Ranked 3rd among pharmaceutical companies for sustainable leadershipRecognized for environmental sustainability, equitable pricing strategies in low- and middle-income countries, and senior executive female representation

14 Global Brands and 12 Potential New Molecular Entities will Drive Sustainable GrowthTakeda Confirms Commitment to Rapid Deleveraging Towards Target of 2x Net Debt / adjusted EBITDA within Fiscal Years Ending March 2022 – March 2024Significant Commitment to and Investment in Carbon Neutrality that Builds on Successful Environmental Sustainability Efforts 

- Selected by the FTSE4Good Developed Index for the 15th consecutive year- Named to the MSCI ESG Leaders Index for the 10th consecutive year- Rigorously evaluated by indices measuring strong performance on ESG criteria

Takeda’s founding mission to serve patients, wherever they are, drives its increased commitments to disease prevention, capacity building, and access to healthcare in developing and emerging countries, in partnership with the global community. Through its annual Global CSR Program, approximately 20,000 employees worldwide cast their votes, selecting City Cancer Challenge, Drugs for Neglected Diseases initiative (DNDi), SeriousFun Children’s Network, UNICEF, and the UN Foundation as 2019 partners.With these programs, Takeda's contributions through its unique Global CSR Program total 10.5 billion yen for a total of 14 programs since its 2016 launch.

Takeda Pharmaceutical Company Limited (“Takeda”) (TSE:4502/NYSE:TAK) today became the first private sector company to announce a financial commitment to the Global Fund’s Sixth Replenishment. The new pledge, consisting of JP ¥ 1 billion over five years, builds on Takeda's previous contribution to the Global Fund. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20190602005021/en/ Takeda, a leading globa